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Fig. 4. (A) A schematic diagram of the Xrx1A-{Delta}FGFR4a construct used to make transgenic tadpoles. (B) Comparison of stage 39 transgenic Xenopus tadpoles carrying the Xrx1A-{Delta}FGFR4a construct (lower two tadpoles) with the sibling that does not carry this construct (upper tadpole). (C) Hematoxylin and Eosin (H&E)-stained section of an eye from a stage 39 Xenopus tadpoles that do not carry the Xrx1A-{Delta}FGFR4a construct. (D) H&E-stained section of an eye from a stage 39 transgenic tadpole carrying the Xrx1A-{Delta}FGFR4a construct, demonstrating disturbed retinal layering.