Fig. 3. 14-3-3 protein misexpression randomizes the localization of XNR1 expression. Control embryos examined for the expression of XNR1 by in situ hybridization exhibit the normal left-sided signal (whole mount in A; section in B). By contrast, embryos receiving injections of 14-3-3E mRNA at the one-cell stage often exhibit bilateral XNR1 expression (whole mount in C; section in D). Red arrowheads indicate expression; yellow arrowheads indicate lack of expression.