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Fig. 5. Reduction in Egfr activity in the PM is sufficient to cause pattern duplications in the DP. (A) Wild-type wing blade. (B-H) Adult wing blades of Ubx-GAL4/UAS-DN-DER (expressed from two copies of the transgene; B), Ubx-GAL4/UAS-Dras1N17 (C-E), Ubx-GAL4/UAS-DN-Raf (F), Ubx-GAL4/UAS-Aos (G) and Ubx-GAL4/UAS-rasN17 (dominantnegative form of mammalian Ras; H) flies. Note pattern duplications (notum-to-wing transformation) in the wing blades and anterior-specific margin bristles in the transformed region. Associated reduction in notum tissue is shown in E. In all wing blades, anterior is towards the top.