Fig. 4. Condensed alveolar structures in biparous
Erbb4Flox/FloxWap-Cre mice. Histological analysis of
Hematoxylin and Eosin stained paraffin wax-embedded biparous
Erbb4+/+Wap-Cre (A,C,E) and
Erbb4Flox/FloxWap-Cre (B,D,F) mammary glands at P13.5
(A,B), P18.5 (C,D) and L1 (E,F). Abnormal secretory activity is indicated by
the accumulation of lumenal lipids in
Erbb4Flox/FloxWap-Cre mammary glands at parturition.
Arrowheads indicate alveolar lumens. Scale bar: 50 µm.