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Fig. 2. Ovaries of TrkC–/– mice contain normal numbers of follicles but those of TrkB–/– mice contain few follicles. This phenomenon is found in ~50% of TrkB–/– mice on either the mixed genetic background or the 129/Sv congenic line, but all ovaries in the C57BL/6 congenic line are affected. Scattergram of number of oocytes in ovaries of TrkB+/+,TrkC+/+ mice (column 1); TrkC–/– mice (column 2); TrkB–/– mice from the original mixed genetic background colony (column 3); TrkB–/– mice from the 129/Sv congenic colony (column 4); and TrkB–/– mice from the C57BL/6 colony (column 5). In column 1, TrkB+/+, TrkC+/+ mouse on C57BL/6 background is represented with a filled square and those on 129/Sv background are represented with open triangles, other mice are of the mixed genetic background. In column 5, filled diamonds represent mice from the seventh generation of the C57BL/6 congenic line of TrkB–/– mice and crosses are mice from the fourth generation.