Fig. 8. Blocking the effects of BDNF and NT4 in culture decreases germ-cell survival and increases germ-cell death. (A,B) The density of healthy oocytes (A), and dying and dead oocytes (B) in ovaries cultured in control medium or in medium containing 10 µg ml^–1 anti-BDNF, 10 µg ml^–1 anti-NT4, and 10 µg ml^–1 each of anti-BDNF and of anti-NT4. Asterisk indicates significant difference compared to untreated control culture, P<0.05.