Fig. 9. Regulation of Smad2 phosphorylation by bon and sur.
Western-blot analysis of wild-type, MZsur, bonMO and
MZsur;bonMO embryos at dome and shield stage. At dome stage,
MZsur and MZsur;bonMO embryos have lower phosphorylated
Smad2 levels but bonMO embryos are not affected. Phosphorylated-Smad2
levels recover by shield stage. Detection of actin serves as loading
control.