Fig. 8. Transplants suggest that lowts213 functions cell
autonomously in neural crest. Prospective hyoid arch neural crest and
hindbrain cells at the level of rhombomeres 4 and 5 (r4 and r5) were
transplanted from donor embryos labeled with a lineage tracer (red) into
unlabeled hosts at 12 hpf (A-C). Lateral views (A'-C') and ventral
views (A''-C'') of mosaic larvae at 65 hpf stained for biotinylated
tracer (brown). (A-A'') Control transplants between wild-type embryos.
(B-B'') Wild-type transplants into low mutants. Arrow indicates
rescued hyoid arch outgrowth on the transplanted side. (C,C')
Transplants of low mutant crest cells into wild-type hosts.
(B''') Rescued muscles of the hyoid arch in low
mutants containing transplanted wild-type neural crest. am, adductor
mandibulae muscle; P2, pharyngeal arch 2 (hyoid arch). Scale bars: 100
µm.