Development -- Wirth et al. 130 (23): 5827 Figure IG9

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.

Fig. 9. Developmental mRNA expression of BDNF, NT3 and NT4/5 in active (SBA+, black bars) and activity-deprived (SBA–, white bars) OTC. (A) BDNF mRNA expression increased with age in active OTC, but remained low in deprived OTC. (B) NT3 mRNA expression was slightly upregulated in young deprived OTC and decreased until 45 DIV. (C) NT4/5 mRNA expression was strongly upregulated in 10 and 20 DIV activity-deprived OTC. The expression levels of the three mRNAs in the 10 DIV SBA+ condition were set to 1.