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Fig. 4. Conditional knockout of Smad4 results in epidermis formation in mammary glands. (A,C,E,G) Skin samples; (B,D,F,H) abscesses found in the fourth gland from a 7.5-month-old Smad4Co/CoWAP-Cre mouse. Markers used for analysis were as indicated. At least 12 abscesses were studied and similar features were observed. Scale bar: 125 µm.