Fig. 2. echinoid interaction with Notch and sca. (A) Light micrograph of N^55e11/+; ed^4.12/ed^4.12 adult thorax. The arrows indicate the positions that macrochaetae should occupy. (B) Immunohistochemical detection of Elav (neurons) in the N^55e11/+; ed^4.12/ed^4.12 pupal thorax. Note that the neurons are arranged in groups rather than singly as expected for wild type. (C,D) Immunohistochemical detection of Sca (green) and Sens (red) in third larval instar wing discs. (C) Wild type. (D) ed^LH23/ed^l(2)k01102. Sca expression is unaffected in the ed mutant background.