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Fig. 3. Bapx1 expression level depends on the Pax1/Pax9 gene dosage. Whole-mount in situ hybridization for Bapx1 on E9.5 (A-D) or E10.5 (E-H) mouse embryos. Genotypes are indicated on top of each panel. w.t., wild type. Note the decrease in Bapx1 staining intensity, as fewer functional copies of Pax1 or Pax9 are present.