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Fig. 3. PDGFR{alpha}fl{Delta}/fl{Delta}; Wnt1Cre+ and Pdgfra-/- neonates and embryos. (A,B) External appearance of NCC conditional mutants after birth. Frontal and ventral view, respectively. The embryo in A is albino; therefore, it lacks pigment in the retinal epithelium. (C) E14.5, PDGFR{alpha} embryo has extensive blebbing (arrowheads) and edema. (D) E13.5, PDGFR{alpha}fl/fl;Wnt1Cre+ possesses the midline facial hemorrhage.