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Fig. 10. Chx10 is necessary for proper regulation of CycD1. The percentage of cells positive for CycD1 is abnormally low in Chx10, Kip1 double null retinas, just as it is in Chx10 single null retinas. Chx10 is therefore necessary for proper CycD1 regulation even when proliferation is significantly restored. **P<0.01.