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Fig. 2. Dorsal closure defects associated with DMYPT mutations. Cuticles of (A) wild-type embryo, (B,C) DMYPT03802 homozygous embryos with different sized dorsal holes; (D) homozygous Df(3L)th102 embryo, (E) Df(3L)th102/DMYPT03802 embryo, and (F) homozygous DMYPT7-51 embryo. DMYPT7-51 is one of the imprecise excision derivatives of DMYPT3727. Anterior is to the left and dorsal is up.