Fig. 3. The basal lamina is disrupted in Dax1 deficient testis at 12.5, 13.5 and 14.5 dpc. Immunohistochemistry with a laminin antibody reveals that laminin deposition clearly separates the testis cords from the peritubular space in wild-type testis (A,C,E); the basal lamina is disrupted or absent in Dax1-deficient testes (B,D,F).