Fig. 5. dap is required to maintain oocyte fate. (A,B) Wild-type and (C-F) dap⁴ clones double labeled with DAPI (A,C,E) to highlight nuclei and BicD antibody (B,D,F). Note that in D, where the dap⁴ oocyte has become highly polyploid, there is little preferential accumulation of the BicD protein. By contrast, in F, where the dap⁴ oocyte has undergone little to no DNA replication, BicD accumulates to levels similar to those observed in wild-type oocytes.