Fig. 3. A gene expression profile during the dauer exit and L1 starvation
timecourses. A self-organizing map was used to cluster the 1984 dauer-specific
genes with common normalized expression patterns into 45 nodes using
1.5x107 iterations. Each row represents the average
expression pattern of the genes in the node (14-100 genes, average of 45). The
columns represent different times during the timecourse except for the first
column (D/L1) which is the ratio of dauer to L1 at 0 hours. The nodes have
also been aggregated into five groups (vertical axis) based on the dauer exit
timecourse expression patterns as labeled. These groups are partitioned into
many nodes because the expression patterns in the L1 starvation timecourse and
relative dauer-enrichment are different. Because normalized data are shown,
there are no units on the scale bar. D, Dauer; L1, L1 larvae. The complete
data are available at
http://dev.biologists.org/supplemental/
and at
http://cmgm.stanford.edu/~kimlab/dauer/