Fig. 6. Fmi is endocytosed. Bottom panels show high magnification images of ommatidia that correspond to the stages represented by the ommatidia in the boxes in top panels. (A) In wild type, Fmi localizes to large vesicles between the nuclei of R3 and R4. (B) In a shi^2ts mutant heat-treated for 2 hours, the large vesicles seen in wild type have been replaced by small puncta decorating membranes. (C) In a hk¹¹ mutant, the large MVB-like vesicles are also replaced with smaller puncta, although they are larger than those seen in shi mutants. Scale bar: 1 µm. Anterior to the right.