(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 10. Heads stained for bone (dark purple) and cartilage (blue) at E18.5. Superior semicircular canal (SSC), tympanic ring (TR) and the basioccipital bone (BO) are marked. In Foxi1+/+ and Foxi1+/- an arrowhead indicates the ossification centers of the middle ear bones. Normal morphology is seen in Foxi1+/+ and Foxi1+/- mice; Foxi1-/- animals display a clearly aberrant integration of the otic capsule in the temporal bone as evident by excessive ectopic cartilage condensation/bone formation in both the cochlea (arrowheads) and the vestibulum (arrows). Scale bar: 200 µm.