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Fig. 4. Histology of inner ears from Foxi1+/+ and Foxi1-/- embryos at E16.5. (A,B) The lateral (LSD) and posterior (PSD) semicircular ducts as well as the endolymphatic duct (ED) are expanded in the mutant ear. (C,D) In the cochlea of Foxi1-/- ear the basal turn (BT) is larger and the apical turn (AT) has formed an apical cyst (AC). Scale bar: 200 µm for A,B; 100 µm for C,D.