Fig. 7. Loss of Hyzic and Cnash expressing cells after treatment with hydroxyurea. (A-C) Hyzic expression after 0 (A), 12 (B) and 18 (C) hours of hydroxyurea (HU) treatment. (D-F) Cnash expression after 0 (D), 48 (E) and 72 (F) hours of HU treatment. (G) Quantitative analysis of loss of cell clusters expressing Hyzic, Cnash and Nowa. Very similar results were obtained by stem cell depletion of the temperature-sensitive mutant sf-1 (Terada et al., 1988). Data shown are mean±s.d. of 15-20 animals.