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Fig. 2. Activity of Cre recombinase in Cre transgenic lines revealed by X-gal staining. (A,B) Wholemounts of E14.5 ROSA26R (A) and K14-Cre43; ROSA26R (B) embryos. Cre activity is detected globally in the epidermis of the K14-Cre43 embryo. (C) Frozen section of K14-Cre43; ROSA26R dorsal skin at P1. (D) Transverse section of E15 bcre-32; ROSA26R embryo torso after whole-mount X-gal staining. Arrows mark the limits of staining in ventral epidermis. HF, hair follicle; NT, neural tube.