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Fig. 7. Induction of ROS: a common pathway in vasculopathy. ROS production and localization in the yolk sac was evaluated by DHE (red) in 8.0 dpc conceptuses treated with D-NMMA (A), L-NMMA (B), L-NAME (C), glucose (D) and glucose plus NOC-18 (E). Images were captured at 20x magnification and merged with DAPI images (n=4).