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Fig. 9. XRAR{alpha}2.2 is required for XCAD3-mediated upregulation of HOXB9. Embryos were microinjected with 10 ng RAR-MO (B), 1 ng XCAD3 mRNA (C) or 10 ng RAR-MO plus 1 ng XCAD3 mRNA (D-F), then allowed to develop until untreated embryos reached stages 18 (A-D,F) or 23 (E), fixed and processed for whole mount in situ hybridization with HOXB9.