Fig. 6. Lmx1a cell-autonomously inhibits formation of dI1 interneurons. (A-H) Chick
spinal cord expressing Lmx1a-IRES-EGFP 48 hours after electroporation.
Visualization of expression of LH2A/B (A), Lim 1/2 (C), Islet 1 (E) and Cath1
(G) (all red) alone or together with GFP (green) (B,D,F,H). Insets show higher
magnifications of boxed regions. Arrowheads point to yellow cells
co-expressing exogenous Lmx1a and Lim1/2 (D) or Islet1 (F). (I-L)
Visualization of expression of Math1 (red) alone (I,K) and together with
endogenous Lmx1a (green) (J,L) in E10.0 wild-type (I,J) and drJ
/drJ embryos (K,L). In drJ
/drJ, embryos, numerous Lmx1a/Math1-double-positive cells
(yellow) are indicated by arrowheads.