Fig. 1. Comparison of Staufen sequences. Amino acid sequence of Xenopus Staufen (XStau) is aligned with human Staufen isoform 1 (hStau1), and Drosophila Staufen (DmStau). Conserved amino acids are boxed in dark gray, and similar amino acids are in light gray; stop codons are denoted by ^*. Identified domains of Staufen are underlined: dsRBD denotes double-stranded RNA-binding domain, PRD denotes proline rich domain, and TBD denotes tubulin-binding domain.