Fig. 6. The sub-cellular distribution of Wg protein in the Wg-producing cells is
altered in ds mutant cells. (A,B) Third instar discs containing
ds38k clones generated by the Minute technique.
Clones were induced during second instar and are marked by the absence of
armZ (red). (A) In ds38k cells, the gradient of
extracellular Wg (green) is expanded with respect to the adjacent wild-type
cells (arrowheads). (B) A cross-section from the region marked by the white
line in A, showing a higher accumulation of Wg protein at the apical surface
of ds mutant cells (compare with wild-type cells, red marker). Wg is
uniformly distributed along the apical-basal axis. Note that the
mislocalization of Wg also affects the wild-type cells adjacent to
ds38k mutant cells (bracket). Wg expression is shown in
the green channel.