Fig. 7. RPTP
acts upstream or in parallel to Delta/Notch signalling
and is required for transcriptional activation of both her1 and
her7. (A) Comparison of deltaC, her1 and her7
expression in RPTPmo embryos, her1 morphants, aei
mutants and embryos co-injected with RPTPmo and her1mo. All
embryos are stained equivalently. (B) Reduction of neither RPTP
nor her1
in a aei mutant background results in an enhancement of the
aei mutant phenotype, indicating a role for RPTP
either
upstream or in parallel to Delta/Notch signalling.