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Fig. 5. Early migration of NCCs in Alk2/Wnt1-Cre mutants. Expression of NCC markers Msx1 (A,B), Foxd3 (C,D) and Sox10 (E,F) in controls (A,C,E) and Alk2 mutants (B,D,F) at E9.0. The expression pattern of Msx1 (A,B; arrows; dorsal view) in the dorsal neural tube is indistinguishable between controls (A) and Alk2 mutants (B). Both Foxd3 (C,D; dorsal view) and Sox10 (E,F; lateral view) are expressed in all three trajectories of migrating NCCs (arrows in C-F) and show no differences between the Alk2 mutants and controls.