Fig. 8. Effects of binocular retinal injections of epibatidine. (A,B) Representative coronal sections of dLGN in P9 rats that received binocular injections of epibatidine (n=3). The retinal fibers of only one eye labeled with CTB-Alexa Fluor 594 (red) are shown, as the other eye projection is identical. The contralateral fibers fill nearly the entire nucleus (A) and the ipsilateral projections are expanded considerably (B). (C,D,E,F) Forty-eight hours after binocular injection of epibatidine, the expression of pERK in retina and dLGN of P7 rats (C,E, n=4) is strongly decreased compared with controls injected with vehicle (D,F, n=3).