Fig. 8. Quantitative analysis of the effect of MET KD transfection on the apical and basal compartment of dendritic arbors. Cortical slices were bombarded with gold particles carrying a combination of either pEGFP and a control empty vector (Ctr) or pEGFP and a vector expressing the kinase-dead MET receptor (METKD). We additionally tested the effect of the dominant negative transfection on cultures supplemented with 200 ng/ml HGF (HGF). The bar charts illustrate percent change in dendrite length and branch number relative to control-transfected neurons. ^*P<0.05, ^**P<0.01 versus control transfections; P<0.001 post-hoc significance between control and MET KD transfections in HGF-treated cultures. Between 40 and 50 individual neurons were analysed under each condition.