Fig. 2. Disappearance of ß1-integrins in glial and neuronal derivatives of NCC. Hu-D immunolocalisation (A,E), DAPI staining (B,F) and ß1-integrin immunolocalisation (C,G) detected in a transverse section of an E13 mutant embryo (A-C) and a control embryo (E-G), at the level of a DRG. Merge pictures are represented in D for the mutant and in H for the control embryo. White arrows and white arrowheads point some of neuronal and glial derivatives, respectively. Note that the two NCC derivatives of the DRG do not express ß1-integrins in the mutant. Structures positives for ß1-integrins in the DRG of the mutant are the vessels, not targeted by the mutation. (I,J) Distribution of ß-galactosidase activity in a transverse section of an E13 mutant (I) and a control (J) embryo, at the level of a DRG. Scale bar: 50 µm.