Fig. 4. Alignment of conserved mouse and human sequence in the necessary and sufficient region of the Mef2c anterior heart field enhancer. Three conserved candidate GATA sites (red shading), two conserved ISL sites (green shading), two candidate E boxes (yellow shading) and a conserved NKE (black box) are noted. The three GATA sites are contained within Fragment 9, while the two ISL sites and the GATA sites are included in Fragment 10. Numbers at the right represent the nucleotide positions within the mouse Mef2c-F6/Frag2 sequence depicted in Fig. 3 and deposited in GenBank (accession number AY324098).