Fig. 7. Wnt8 and zygotic BMP both regulate vent and vox, but do so differently. In
situ hybridization for gsc (A,B,F,G), vent (C-E),
vox (H-J), wnt8 (K,L) and bmp2b (M-O).
Genotypes/treatments are indicated above each panel. Note circumferential
gsc in vent;vox (A) and wnt8;swr (B,G) double
mutants/morphants, and the strong reduction of vent (E) and
vox (J) in wnt8;swr.
wnt8 is still expressed in swr mutants (L), and bmp2b
is still expressed in wnt8 mutants/morphants (N,O). Arrowheads in M-O
indicate the dorsal limits of mesodermal bmp2b, which is shifted
slightly ventrally in wnt8 mutants/morphants (N,O). Embryos shown are
at shield stage, animal view, dorsal right.