Development -- Hecksher-Sørensen et al. 131 (19): 4665 Figure IG8

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Fig. 8. Expression of FGFs in the SMP at E10.5. (A,B) Both Fgf9 and Fgf10 are expressed in the SMP and underlying mesenchyme. Fgf10 is expressed in the ventral domain of the SMP and to a lesser extent in the mesenchyme between the dorsal pancreas and the SMP (A). Fgf9 (B), and its high affinity receptor Fgfr3 (C), are expressed in the dorsal region of the SMP and towards the tip of this structure as it develops in a leftward direction. In the Bapx1^–/– mutant (D), Fgf10 is downregulated in the ventral SMP, but is still detectable in the underlying mesenchyme.