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Fig. 11. Gata2 and Gata3 do not control the central noradrenergic phenotype. (A-C) The anlage of locus coeruleus (LC) visible in the dorsal metencephalon by anti-Phox2a immunohistochemistry (A) expresses neither Gata2 (B) nor Gata3 (C) at E10.5. (D-G) At E13.5 the anlage of the LC, visible by in-situ hybridisation for Dbh (F) expresses neither Gata2 nor Gata3 (arrowhead in D and E, respectively) and is intact in Gata3 mutants (G).