Fig. 1. Progressive pigmentation in orJ retinas. (A-H) Eyes
were sectioned to analyze for pigmentation in orJ/+
heterozygous (A,C,E) or orJ/orJ homozygous
(B,D,F,G,H) littermates. Ages are indicated on the figure. (A,B) Insets show a
full section of the eye (note scale bar differences). (B,D,F) Arrows indicate
the central limit of ectopic pigmentation in the retinas of
orJ mutants. (D) The lens is marked by a thin black line
in the orJ eye at E17.5. (G,H) The peripheral retina in
orJ mutants shows ectopic pigmentation, increasing over
time until most of the retina appears pigmented at P15. (H) The presumptive
retina is marked with arrowheads. Scale bar is 100 µm.