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Fig. 2. The epicardium is present in Hhex–/– mice. Cross-sections through the ventricular region of E11.5 hearts from (A) Hhex+/+ and (B) Hhex–/– mice. Immunohistochemistry for pan-cytokeratin was performed. Green staining and arrows indicates the cells that are cytokeratin-positive and therefore epicardial cells.