Fig. 7. Expression of cyclin D1 under normal conditions and upon inhibition of Wnt signaling. (A,B) Normal expression patterns of cyclin D1 in the neural tube at (A) a segmental plate (SP) level and (B) opposite dissociating somites (DS). In A, cyclin D1 mRNA is expressed throughout the neural tube, except for the floor plate and dorsal midline. (B) At more rostral regions, cyclin D1 signal becomes apparent in premigratory and early emigrating NC cells (arrowheads). (C,D) Electroporation of ß-catenin fused to the engrailed repressor domain downregulates unilaterally expression of cyclin D1 as shown in whole-mount (C, electroporation between arrows) and (D) transverse section (^*treated hemi-tube). Scale bar: 35 µm in A,B,D.