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Fig. 8. Wnt1 and Wnt3a expression are decreased in Bmpr double knockout animals. (A) In normal animals, Wnt1 is expressed in the roof plate and adjacent neural ectoderm at 10.5 dpc. (B) In double mutant animals, Wnt1 expression is restricted to the roof plate. (C) In normal animals, Wnt3a is expressed in the roof plate and adjacent neural ectoderm. (D) Wnt3a in double mutants is not expressed in the neural ectoderm, but roof plate expression appears unaffected at 10.5 dpc.