Development -- Devenport and Brown 131 (21): 5405 Figure IG1

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Fig. 1. Mutation of the gene that encodes the ß ${nu}$ integrin subunit. (A) ß ${nu}$ genomic region. The transposon insertion EP(2)2030 was used to create imprecise excisions that partially delete the ß ${nu}$ locus. The ß ${nu}$ ¹ deletion removes the first 69 amino acid codons while ß ${nu}$ ² removes the first eight and $~$ 2 kb upstream regulatory sequence. Neither allele affects surrounding genes. (B) In situ hybridization against ß ${nu}$ transcripts in wild-type and ß ${nu}$ ² embryos demonstrates that ß ${nu}$ ² mutants do not make any detectable transcript. (C) Adult flies homozygous for ß ${nu}$ ¹ and ß ${nu}$ ² are viable, and have no obvious morphological defects.