Fig. 8. wg activation in normal apoptotic cells. (A-B) Untreated wing disc of genotype wg-Gal4>UAS-lacZ doubly stained with the anti-Wg antibody (red) and anti-ß-gal (green). The wg and lacZ domains are largely coincident; the relative expansion of the lacZ domain is probably the result of the greater stability of the ß-gal protein. (C-D) Irradiated disc of the same genotype fixed 24 hours after X-rays and stained for caspase 3 and ßgal. The dots of ß-gal staining reflect wg activation in apoptotic cells that induces UAS-lacZ activity.