Fig. 5. Growth retardation in coll2a1-Cre, Fosl2f/f mice. (A)
X-ray analysis of a 23-day-old coll2a1-Cre, Fosl2f/f mouse
and littermate control (arrowhead indicates kyphosis). (B) Decreased body size
and body weight of coll2a1-Cre, Fosl2f/f mice at P10. Bars
represent mean value±s.d.; n=5;
*P<0.05. (C) PCR for Fosl2 deletion in tissues
and organs of a 6-day-old coll2a1-Cre, Fosl2f/f mouse. The
same deletion efficiency was observed in older mice. he, heart; li, liver; lu,
lung; ki, kidney; sp, spleen; br, brain; th, thymus; ln, lymph node; mu,
muscle; sk, skin; st, stomach; in, intestine; bm, bone marrow; sm, sternum;
cv, calvariae.