Fig. 5. Gene structures of the ncr-1 and ncr-2 loci and reporter constructs. (A) Structure of ncr-1A and ncr-1B cDNA isoforms. Black boxes represent coding and white boxes represent non-coding exon sequences. The genomic subclone represented by ncr-1A rescued the ncr-2; ncr-1 Daf-c phenotype. Also shown are corresponding positions of the original nr2022 deletion allele and additional mutations isolated from our noncomplementation screen. (B) Structure of ncr-1 reporter constructs and corresponding expression patterns. (C) Structure of ncr-2-coding region and position of nr2023 deletion allele. The corresponding genomic fragment rescued the ncr-2; ncr-1 Daf-c phenotype. (D) Structure of the ncr-2 reporter construct and its expression pattern.