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Fig. 5. Constructs that cause transcriptional activation (six1VP16; six1+eya1) reduce keratin expression (A,B), expand the placodal domain of sox11 (E,F) and expand the foxD3 domain (I,J). Constructs that cause transcriptional repression (six1EnR; six1+groucho) reduce keratin expression (C,D), reduce sox11 placodal expression (G,H) and reduce the foxD3 domain (K,L).