Fig. 7. bicoid mRNA localisation during late oogenesis. In situ hybridisation showing bicoid mRNA localisation in confocal sections of stage 12 egg chambers. (A) In the wild-type bicoid mRNA accumulates at the anterior of the oocyte. (B) Although bicoid mRNA is detectable at the anterior of exu null mutants most of the mRNA appears to be unlocalised at the cortex or in the ooplasm. (C) In mutants in which Exu phosphorylation is abolished, bicoid mRNA is enriched at the anterior indicating partial recovery of the complete loss of bicoid mRNA localisation during mid-oogenesis. Genotypes are indicated. All females were grown at 18°C. Anterior is leftwards; posterior is rightwards.