Fig. 3. vab-8 and unc-51 act autonomously in the CAN cell. vab-8 or unc-51 full-length cDNAs was expressed from the ceh-23 promoter. At the top is a schematic representation of the posterior half of C. elegans, showing a CAN cell body and its posterior axon. Also shown are two sensory neurons (PHA/B) that express the Pceh-23::gfp transgene and mark the position where the CAN axon terminates. We scored the extent to which the posterior axons extended, with the position of the CAN cell body representing 0% extension and the position of the PHA/B sensory neurons representing 100% extension (see Materials and methods). The numbers in the boxes represent the percentages of axons that terminated or turned in that interval. Axons that completed 95-100% of the distance from the CAN cell body to the sensory neurons are considered wild type. n is the number of axons scored. To simplify the statistical analysis, only percentages of the wild-type axons (to the right of the vertical line) were compared. ^*The two-tailed Z test was used to compare the differences in the distributions of the two populations of axons in the wild-type position.