Fig. 6. The localization of MBD2/3 depends on DNA methylation. (A) Embryos were
demethylated with the DNA methyltransferase inhibitor 5-azacytidine and double
immunostained with antibodies against MBD2/3 (green) and DNA (red). This
caused a readily detectable displacement of MBD2/3 from DNA. (B) For
comparison, pictures from mock-treated embryos are also shown. Scale bars: 25
µm, insets show fourfold magnified details.