Development -- Harmon et al. 131 (24): 6163 Figure IG7

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Fig. 7. Pancreatic expression of HES1 in Gdf11-deficient mice. (A-C) Expression of HES1 (black nuclei) in Gdf11^+/+, Gdf11^+/- and Gdf11^-/- mice at E17.5. (D) Quantification of HES1⁺ nuclei per mm² tissue. The difference in numbers of HES1⁺ nuclei in Gdf11^+/+, Gdf11^+/- and Gdf11^-/- mice is not significant (NS). (E,F) Gdf11 expression (rust brown) detected by in-situ hybridization in Hes1^+/+ and Hes1^–/– pancreata at E15.5.